CONCEPT OF DISEASE (Epidemiologic triad & Rothman’s Causal Pies)

A. Disease: Any harmful deviation from the normal functional/ structural state of an organism/ person.  The normal state of the organism (human/plant) represents the condition of physiological balance (homeostasis). B. Epidemiologic triad The traditional model for infectious disease:- Interaction of these three factors is necessary to initiate the

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Mycobacterium leprae: Types of Leprosy, Pathogenesis & Epidemiology of leprosy

Leprosy is a chronic bacterial disease and it is caused by Mycobacterium leprae. Leprosy was first observed by Hansen in 1868 so also known as Hansen disease. It mainly affects the skin, eyes, nose and peripheral nerves. It is a gram-positive acid-fast bacteria for which 5%

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