1. Appearance
- The medicated Gels can be examined physically for appearance like clarity, colour and presence of any particle.
2. Skin irritation
- Skin Irritation is determined by applying the gel on the skin of healthy volunteers.
- No irritation: 0
- Slight irritation: 1
- Irritation: 2
3. pH
- pH of Gels can be measured using digital pH meter.
- Standard pH of gel is 5 to 5.5.
4. Viscosity
- Viscosity was determined using Brookefield viscometer.
5. Drug content
- Determined by appropriate spectrophotometrically like uvspectrophotometer.
6. Spreadability
- Spreadability is measured by spreading 0.5 g Gel on a circle of 2 cm diameter on a glass plate. Then a second glass plate is placed. 1/2 kg weight placed on the upper glass plate for 5 minutes.
- Finally diameter of circle spreading is measured.
S = ML/T
M= weight of an upper side
L= length of circle/ diameter
T= time in minutes
S=Spreadibility
7. Stability
- Also known as shipping test.
- It is performed to determine stability of Gel at various temperatures and RH (Relative humidity). Read more – stability Test
📢 Join Our Pharma Community
Stay updated with Pharmacy Previous Papers, Pharma Jobs, GPAT Notes, Study Materials, Admission Alerts & Pharma News.
Join WhatsApp Channel
Get instant updates on Pharmacy Previous Year Papers, Pharma Job Notifications, Study Materials, Admission Alerts and Pharma News.
Join WhatsApp
Join Telegram Channel
Receive latest updates about Pharmacy Previous Papers, Pharma Jobs, GPAT Materials, Admissions, Notes and Pharma News.
Join TelegramJoin Telegram Group
Download FREE Books & Notes, D.Pharm, B.Pharm, M.Pharm, GPAT, Drug Inspector Previous Papers and much more.
Join Group