Scientists Recruitment 2020 (Pharma), CDRI-Lucknow

The Pharmapedia

Central Drug Research Institute, Lucknow, a premier Institute under Council of Scientific and Industrial Research (CSIR), is involved in multidisciplinary R&D programs of both basic and applied nature. CSIR-CDRI is a pioneer biomedical research organization in India and has the infrastructure and expertise to develop a drug from concept to commercialization. In the year 2012, CSIR-CDRI shifted to its state of the art new campus, which has been set up with a vision to serve as a Nodal Center of CSIR in new drug discovery and development. Spread across ~61 acres, it houses an R&D Complex, Support Services, Guest House, Hostel and Staff Quarters.

Applications are invited from motivated young Indian Nationals with requisite qualification and experience for the following posts as per the details given below.

Details of Vacancy:

1. Scientist 06 [UR-3; SC-1; OBC-1; EWS-1] & 02 PwD (OH/HH/VH) Backlog Posts
Basic pay: Rs. 67700/-; Emolument: Rs. 94,720/- Age limit: 32 years
2. Senior Scientist 08 UR/Lateral Entry
Basic pay: Rs. 78800/-; Emolument: Rs. 1,08,928/- Age limit: 37 years
3. Principal Scientist 01 UR/Lateral Entry
Basic pay: Rs. 123100/-; Emolument: Rs. 159744/- Age limit: 45 years
Post Code: 001
Area: Neurobiology
Post: Scientist 1 UR
Age limit: 32 Pay Matrix Level-11 Rs.67700/-
Qualification: MVSc / MD or equivalent in pharmacology or medicine or pediatrics or neurology OR PhD in areas related to neurobiology (thesis submitted)
Desirable Experience: Experience in whole cell patch clamp on isolated cells and brain slices, hERG ion channel recording on isolated cells/ electrophysiology, neurobehaviour, experience in neurodegenerative disorders
Job Specification: Regulatory Patch clamp studies for hERG liability, establish and support the neurophysiological parameters for cognitive impairment and emotional deficit
Post Code: 002
Area: Virology
Post: Senior Scientist 1 UR
Age limit: 37 Pay Matrix Level-12 Rs.78800/-
Qualification: MD/MVSc with 3 years’ research experience in virology OR PhD in any area of life sciences with 2 years’ research experience in virology OR MBBS +PhD in areas related to viral infection
Desirable Experience: Experience in the area of human pathogenic viruses, addressing infection mechanisms, host-virus interaction, diagnostics and antiviral therapeutics.
Job Specification: Set-up a virology research laboratory with BSL2 containment on viral diseases of national priority. Develop independent research program.
Post Code: 003
Area: Host-pathogen interactions
Post: Senior Scientist 1 UR
Age limit: 37 Pay Matrix Level-12 Rs.78800/-
Qualification: MD/MVSc) with 3 years’ research’ experience in Virology or Pathology or Immunology or Microbiology
OR
PhD in any area of life sciences with 2 years’ research experience in infectious disease biology.
OR
MBBS +PhD in an area of life sciences
Desirable Experience: Experience and contribution towards understanding host immune evasion and regulation of host cellular processes by pathogens (parasites—malaria and other apicomplexans or leishmania/ microbes), experience with pathogen culture and animal infection models, interest in approaches for host-directed therapy.
Job Specification: To establish a robust research program in the area of host-pathogen interface, contribute to evaluation of in vivo efficacy of hit/lead compounds.
Post Code: 004
Area: Host-pathogen interactions
Post: Scientist 1 SC 1 PWD-OH/HH/VH
Age limit: 32 Pay Matrix Level-11 Rs.67700/-
Qualification:
MVSc virology or microbiology / MD microbiology or immunology
OR
PhD in an area of life sciences (thesis submitted)
Desirable Experience: Experience and contribution towards understanding host immune evasion and regulation of host cellular processes by pathogens (parasites—malaria and other apicomplexans or leishmania/ microbes), experience with pathogen culture and animal infection models, interest in approaches for host-directed therapy.
Job Specification: To establish a robust research program in the area of host-pathogen interface, contribute to evaluation of in vivo efficacy of hit/lead compounds.
Post Code: 005
Area: Human genetics
Post: Senior Scientist 1 UR
Age limit: 37 Pay Matrix Level-12 Rs.78800/-
Qualification:
MD with 3 years’ research experience in clinical genetics or physiology or medicine
OR
PhD in an area of life sciences with 2 years’ of research experience in the area of human genetics transcriptomics, proteomics and FISH with an ability to analyze drug effects and toxicity
Desirable Experience: Experience in the analysis of chromosomal anomalies – genetic or chemical/drug induced, genome analysis, transcriptomics, proteomics and FISH with an ability to analyze drug effects and toxicity
Job Specification: Design & conduct experiments on genome analysis, transcriptomics, proteomics and FISH to analyze drug effects and toxicity
.

Post Code: 006
Area: Endocrinology
Post: Senior Scientist 1 UR
Age limit: 37 Pay Matrix Level-12 Rs.78800/-
Qualification:
MD/MVSc with 3 years research experience in endocrinology.
OR
PhD in an area of life sciences with 2 years’ research experience in endocrinology
OR
MBBS + PhD in endocrinology
Desirable Experience: Experience in the following area: a) organization of growth plate and regulation of chondrocyte differentiation, b) patterning and morphogenesis of bones and joints and c) joint tissue remodelling pathways leading to tissue damage, and identification of new therapeutic targets.
Job Specification: To undertake research in the areas of bone and joint physiology and pathophysiology leading to the discovery of therapeutic targets.
Post Code: 007
Area: Analytical Biochemistry
Post: Principal Scientist 1 UR
Age limit: 45 Pay Matrix Level-13 Rs.123100/-
Qualification:
MD/MVSc with 5 years’ research experience in biochemistry
OR
PhD in an area of natural sciences with 3 years’ research experience in biochemistry
OR
MBBS + PhD in an area of natural sciences with 3 years research experience in clinical biochemistry
Desirable Experience:
Experience in developing diverse methods of bioactive enzyme/protein expression, isolation, characterization, enzyme kinetics, receptor-ligand (small molecule and peptide) interactions; in particular membrane receptor-ligand interactions, biochemical assay development. Expertise in Surface Plasmon Resonance and isothermal calorimetry.
Job Specification: Conduct an independent research program in biochemical aspects of infectious or lifestyle diseases; contribute to development of biochemical assays for discovery and development of novel therapeutics.
Post Code: 008
Area: Computational Chemistry
Post: Senior Scientist 1 UR
Age limit: 37 Pay Matrix Level-12 Rs.78800/-
Qualification:
PhD in an area of chemical sciences/ chemical biology/ computational biology , with 2 years’ research experience in computational chemistry.
Desirable Experience:
Demonstrated skills in the application of computer-assisted drug design using standard modeling and computational software packages; scientific programming experience including machine learning approaches to address drug discovery problems; Advanced knowledge of computational chemistry principles and knowledge of how to apply these to pharmaceutical research projects; Exposure to other disciplines of relevance to drug discovery, such as synthetic organic chemistry, biology, pharmacology, toxicology, biochemistry, or physical chemistry. Experience with programming and/or scripting languages and/or chemically aware databases and have relevant experience of the computational application of molecular quantum chemical techniques, especially density functional theory.
Job Specification: Support of drug discovery projects by developing and delivering timely, high-quality computational solutions and impacting project teams through understanding target-ligand binding, structure based and ligand-based lead optimization, virtual screening, library design and ADME in-silico modeling. Participate in interdisciplinary project teams and play a key role in compound design. Apply molecular modeling, conformational analysis, homology modeling and pharmacophore hypothesis generation to compound design. Develop hypotheses to understanding drug binding and SAR by application of molecular dynamics. Compound library design and the application of virtual screening to identifying new lead material. Develop ML/AI models as required to support team initiatives.
Post Code: 009
Area: Medicinal Chemistry
Post: Scientist 1 EWS
Age limit: 32 Pay Matrix Level-11 Rs.67700/-
Qualification: PhD in any area of chemical sciences (thesis submitted)
Desirable Experience: Demonstrated comprehensive and state of the art knowledge in modern synthetic methodologies as well as a basic understanding of molecular properties of chemical compounds. Motivated effort towards designing chemical compounds for biologically activity against diseases, prioritize target compounds and plan and execute their synthesis Analyze the data sets to generate structure-activity relationships within the chemical library. Working knowledge of separation and spectroscopic techniques. A record of publications and patents demonstrating proficiency in synthetic chemistry leading to drug discovery in Chemistry/ Pharmacology journal
Job Specification: Design and synthesize novel chemical compounds to optimize potency, selectivity, pharmacokinetics, and in vivo efficacy. Interface with the biological and pharmacological collaborators in the testing and development of interesting compounds. Gain knowledge and expertise in use of state-of-the-art in silico modeling tools for hypothesis driven design of novel compounds and exploration of structure-activity relationships.
Post Code: 010
Area: Process Development Chemistry
Post: Scientist 1 UR
Age limit: 32 Pay Matrix Level-11 Rs.67700/-
Qualification:
ME / MTech. in chemical engineering
OR
BE/BTech in chemical engineering with Advanced Diploma from AcSIR with distinction
OR
PhD in chemical sciences (synthetic organic/bioorganic/ medicinal /pharmaceutical chemistry) (thesis submitted)
Desirable Experience: Industrial experience in process chemistry /pilot plant in the area of drug/pharmaceutical agents would be an added advantage;
Job Specification: To develop synthetic routes that are efficient, safe, cost-effective, environmentally friendly, and industrially viable for biologically active leads, drug intermediates or drug candidates
Post Code: 011
Area: Pharmaceutical & Biomedical analysis
Post: Senior Scientist1 UR
Age limit: 37 Pay Matrix Level-12 Rs.78800/-
Qualification:
Ph.D. in related areas of pharmaceutics with 2 years’ research experience in pharmaceutical and biomedical analysis.
Desirable Experience: Ph.D. thesis incorporating development and validation of bioanalysis by HPLC or LC-MS or LC-MS/MS; experience in the pharmaceutical industry/CRO in development and validation of HPLC and LC-MS/MS analytical and bioanalytical methods for pharmacokinetics, metabolite identification and biodistribution; OR Post-doctoral research experience, published work of high quality in respect of pharmaceutical and biomedical analysis; experience in animal handling, experience in regulatory filing for investigational new drugs or generic drug products; OR Approved Chemist (by State Licensing Authority/CDSCO).
Job Specification: Develop and validate analytical methods for API, formulations, blood plasma/serum and tissue samples as per drug regulatory requirements, design and conduct of clinical and preclinical studies on pharmaco-kinetics in rodents and non-human primates, pharmacokinetic modeling, metabolite identification, preparation of regulatory submissions for CDSCO, US FDA, EMA, MHRA, ANVISA, Rosdravnazor, etc.
Post Code: 012
Area: Statistics
Post: Senior Scientist 1 UR
Age limit: 37 Pay Matrix Level-12 Rs.78800/-
Qualification:
PhD (Biostatistics or Statistics) with 2 years’ research experience in statistical application to biological/clinical sciences.
Desirable Experience: Experience of statistical application to biological/clinical sciences, analysis of genome variation and epidemiology data.
Job Specification: Analysis of research and pre-clinical/clinical data as per regulatory requirements
Post Code: 013
Area: Analytical Chemistry (Mass Spectrometry)
Post Senior Scientist 1 UR
Age limit: 37 Pay Matrix Level-12 Rs.78800/-
Qualification:
PhD in any area of natural sciences with 2 year research experience in use of Mass Spectrometry instruments
Desirable Experience: Experience in the field of Mass Spectrometry. Expertise with a few of the following techniques: Triple quadrupole MS/MS, Q- TOF-MS/MS, Orbitrap MSn and MALDI TOF/TOF. Management, maintenance and application of sophisticated Mass instruments coupled with HPLC or UPLC. Working experience on protein characterization and/or the development and validation of analytical methods using the LC-MS/MS instruments in complex matrices.
Job Specification: Develop an independent research program; conduct analysis of samples using mass spectrometry for identification, characterization and quantitation of small molecules and large biomolecules as per ICH, NABL and GLP guidelines.
Post Code: 014
Area: IPR Management & Business Development
Post: Scientist 1 UR
Age limit: 32 Pay Matrix Level-11 Rs.67700/-
Qualification: B-Tech in biotechnology or chemical technology/ MSc with PG degree in Intellectual Property Law (Ist class or 60% on an aggregate or equivalent GPA);
OR
PG diploma in patent law/IP laws/IPRs/ Business management
OR
PhD in Pharmaceutical sciences/ Life sciences/ Chemical Sciences (thesis submitted)
Desirable Experience: Registered Patent Agent
OR MBA in pharmaceutical management/ technology management. Understanding of scientific documentation with 2 year experience in IPR management, technology transfer, technology marketing, negotiations with excellent communication and writing skills.
Job Specification: Act as an interface between scientists and industry/ government agencies/ R&D institutes/ international agencies etc. and undertake liaison activities for promotion of research & business development/ translational research and institutional programs.
Post Code: 015
Area: HR Management
Post: Scientist 1 OBC, 1 PWD-OH/HH/VH
Age limit: 32 Pay Matrix Level-11 Rs.67700/-
Qualification: PhD in any area of natural/ pharmaceutical Sciences (thesis submitted)
MBA / Post-graduate degree in HR management or Public Relations / Mass communications with aptitude for original science writing for mass media.
Desirable Experience: Proficiency in organization, writing and communication skills.
Job Specification: Coordinate trainings, skill development programs & societal activities; Plan and execute science outreach;
Manage technical information, social media, public relations and mass communication,
institutional publications and publicity material.

Important Date:

Eligible candidates are required to fill the application form ONLINE by accessing the website https://recruit.cdri.res.in or accessing the link ‘SCIENTIST RECRUITMENT-2020’ available on CDRI website https://recruit.cdri.res.in The printout of the application, generated after Online submission is to be sent to CDRI with all the relevant enclosures before 15 January, 2021, 23.59 Hrs.


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