1.Flocculation: Neighboring globals come closer to each other ⇒ forms Flocs Re-Dispersed on shaking Prevented by imparting charges on globules and using uniform-sized globules 2.Creaming: Occurs Due to the density difference Upward creaming-O/W emulsion Downward creaming-W/O emulsion If Creaming occurs, Drug is not uniformly distributed ⇒ variable in dosage ⇒ emulsion should be shaken for … Continue reading Physically Instability of Emulsion | Pharmacy Notes