Q.101) In context to voltammetry, which of the following statement is false
[a] Technique can be used to analyse organic compounds containing carbonyl groups
*[b] Organic solvents cannot be used as aqueous organic mixture in this technique
[c] Immuno sensors are available in voltammetry
[d] Triangular waveform is used for excitation of solution in cyclic voltammetry
Q.102) Which of the following Urinary Tract Anti-Infective agents requires an acidic pH of urine for optimum action
[a] Gentamicin
[b] Erythromycin
*[c] Carbenicillin
[d] Streptomycin
Q.103) The molecule having zero dipole moment is
*[a] BF3
[b] HF
[c] NH3
[d] CH3CI
Q.104) As the solution of a strong electrolyte is diluted, the following phenomenon is observed
*[a] The specific conductance decreases and equivalent conductance increases
[b] The specific conductance increases and equivalent conductance decreases
[c] Both specific conductance and equivalent conductance increase
[d] Both specific conductance and equivalent conductance decrease
Q.105) Alzheimer’s disease is mainly because of the neurodegeneration of the following part of the brain
[a] Hypothalamus
[b] Midbrain
*[c] Hippocampus
[d] Cerebellum
Q.106) Choose the correct and the major product formed in the above-given reaction from the choices listed below
[a] 2-Pentene
*[b] 2-Methyl-2-butene
[c] 1-Pentene
[d] 1-Methyl-2-butene
Q.107) Which of the following molecular properties can be determined by Thermogravimetric Analysis
[a] Solubility
*[b] Hygroscopicity
[c] Colour stability
[d] Hydrolysis
Q.108) Which of the following levels of IVIVC is represented by “the relationship between one dissolution time point (e.g. t 50%) and one mean pharmacokinetic parameter, such as AUC, Tmax or Cmax
[a] Level A
[b] Level B
*[c] Level C
[d] Level D
Q.109) Which of the following metabolite is used to inactivate the vasicotoxic metabolites leading to hemorrhagic cystitis by alkylating agents used in the treatment of cancer
[a] Acroline
[b] Aldophosphamide
[c] Cyclophosphamide
*[d] Mesna
Q.110) The difference in velocity between two planes of liquids separated/infinitesimal distance is called
*[a] Rate of shear
[b] Rate of flow
[c] Rate of force
[d] Shearing stress
Q.111) Which one is not the characteristics of the Hexose Monophosphate Pathway
[a] It produces CO2
*[b] It requires ATP for phosphorylation
[c] It is controlled by inhibition of glucose-6 phosphate dehydrogenase by NADPH
[d] It produces ribose-5-phosphate
Q.112) Which of the following drugs has an apparent volume of distribution approximately 6500 litres
[a] Amoxicillin
[b] Ibuprofen
*[c] Chloroquine
[d] Diazepam
Q.113) Which of the following hyperlipidemic drugs act via a GPCR
*[a] Nicotinic acid
[b] Fenofibrate
[c] Atorvastatin
[d] Ezetimibe
Q.114) Under which of the following conditions in-vitro-in-vivo correlation for a drug fails
*[a] When the drug is highly soluble
[b] When the drug’s absorption takes place by a complex process
[c] When the dissolution medium is adequately simulated
[d] When the drug is highly permeable but poorly soluble
Q.115) Which of the following pharmaceutical solvent has the highest dielectric constant, at 25 degree C
*[a] Glycerin
[b] Ethanol
[c] Acetone
[d] Phenol
Q.116) Which of the following is true for bone tissue cell differentiation and maturation
*[a] Osteogenic → Osteoblasts → Osteocytes
[b] Osteogenic → Osteoblasts → Osteoclasts
[c] Osteocytes → Osteogenic → Osteoblasts
[d] Osteoclasts → Osteoblasts → Osteocytes
Q.117) Which of the following drug can produce mydriasis without Cycloplegia
[a] Atropine
[b] Tropicamide
[c] Homatropine
*[d] Ephedrine
Q.118) The law of relative lowering of vapour pressure was given by
*[a] Raoult
[b] Ostwald
[c] Henry
[d] Van’t Hoff
Q.119) Which one of the following compound is a precursor for the biosynthesis of cholesterol
[a] Progesterone
*[b] Lanosterol
[c] Cholic acid
[d] Coprostanol
Q.120) Basic dyes are used in microbiological staining. Which of the following statement is wrong about mechanism of staining
[a] The positive ions on the surface of bacteria form a colored complex with the dye
[b] Ionic exchange between the negative charge on the bacteria and positive charge of dye takes place
[c] Ionic exchange between the positive charge on the bacteria and negative charge of dye takes place
*[d] The neutral charge on the surface of bacteria forms a colored complex with the basic dye