Q.40) Select the correct set of anticancer drugs that belong to “Pyrimidine and related compounds”
*[a] 5-Fluorouracil, Tegafur, Decitabine, 5-Azacytidine
[b] 5-Fluorouracil, Tegafur, Decitabine, Clofarabine
[c] Tegafur, Decitabine, 5-Azacytidine, Clofarabine
[d] Tegafur, Decitabine, 5-Azacytidine, Pentostatin
Q.41) Establishing a complete structure of __________ is more complex problem than others
*[a] Polysaccharide
[b] Protein
[c] Nucleic acid
[d] Peptide
Q.42) Which of the following Climatic Zones (As per WHO Criteria) refers to “Hot and Humid climate”
[a] Zone 1
[b] Zone II
[c] Zone III
*[d] Zone IV
Q.43) Match the following Ayurvedic formulations under Column I with the process/ properties under Column II and choose the correct options
| List 1 | List 2 |
| Immune System | Functions |
| 1. Mast cell | [P] Master of Immune system |
| 2. Lymphocytes | [Q] Allergic reactio |
| 3. T-cells | [R] Cell mediated immune reaction |
| 4. Monocytes-Macrophages | [S] Antigen recognition, Phagocytosis |
Choose the correct answer from the options given below
[a] 1-[P], 2-[R], 3-[S], 4-[T]
[b] 1-[R], 2-[Q], 3-[P], 4-[S]
[c] 1-[R], 2-[T], 3-[P], 4-[Q]
*[d] 1-[Q], 2-[R], 3-[S], 4-[P]
Q.44) The interfacial forces are related to the contact angle by
[a] Nernst Equation
[b] Stoke’s Equation
*[c] Young’s Equation
[d] Laplace Equation
Q.45) A mixture of p-anisaldehyde and formaldehyde in the presence of concentrated sodium hy droxide results in
[a] p-Methoxy sodium benzoate
[b] Sodium-p-methoxy benzene
*[c] P-Methoxy benzyl alcohol
[d] p-Methoxy benzoyl alcohol
Q.46) A component of film-coating solution to make film more pliable, enhance spread over tablets, beads and granules is called
[a] Adsorbent
[b] Humectant
[c] Stiffening agent
*[d] Plasticizer
Q.47) Following is an example of atypical anti-psychotic
[a] Haloperidol
*[b] Clozapine
[c] Thioridazine
[d] Fluphenazine
Q.48) Haemophilus influenzae type B (Hib) vaccine is an example of
[a] Subunit vaccine
[b] Toxoid vaccine
[c] Recombinant protein vaccine
*[d] Conjugate vaccine
Q.49) Which one among the following drugs has the IUPAC name, α, α, α,α- tetramethyl 5- (1 H-1,2,4-triazole- 1- ylmethyl)-1,3-benzenediacetonitrile
[a] Letrozole
*[b] Anastrozole
[c] Exemestane
[d] Aminoglutethimide
Q.50) Invert sugar is a product obtained by the hydrolysis of
[a] Maltose
*[b] Sucrose
[c] Lactose
[d] Dextrin
Q.51) Following groups exert anyone of the effects on electrophilic aromatic substitution
Identify whether all three are
[a] Weakly activating
[b] Deactivating
*[c] Moderately activating
[d] Strongly activating
Q.52) All the following are true with Metoclopramide EXCEPT
*[a] 5-HT1 receptor antagonist
[b] D receptor antagonist
[c] 5-HT3 receptor antagonist
[d] 5-HT4 receptor agonist
Q.53) What do you mean by Orphan drug
[a] A drug meant to be distributed among the orphans who can not afford the cost of the drug
[b] A drug for a disease which is not having any other treatment options at all
*[c] A drug which is useful for rare disease
[d] A drug that is available in abundance
Q.54) Requirements of factory premises for the manufacture of cosmetics are mentioned, in the Drugs and Cosmetics Rules, 1945 under
[a] Schedule M
[b] Schedule M-1
*[c] Schedule M-2
[d] Schedule M-3
Q.55) A reagent may attach itself to a conjugated diene to the carbons at the two ends of the conjugated system. Identify the reaction involved from the following
[a] 1,2-addition
*[b] 1,4-addition
[c] 1,3-addition
[d] 2,4-addition
Q.56) The reaction between naphthalene and chromium trioxide in the presence of glacial acetic yields
*[a] Naphthalene-1,4-dione
[b] 4-Hydroxynaphthalen-1(4H)-one
[c] Naphthalene-1.2-dione
[d] 1-Hydroxynaphthalen-2(1H)-one
Q.57) Given below are two statements, one is labelled as Assertion and the other is labelled as Reason
Assertion (A) The disadvantage of atomic absorption spectroscopy is the need for each element to be analysed
Reason (R) As atomic absorption spectrophotometer uses different halo cathode lamp for each element, it is very specific for an individual element under test
In light of the above statements, choose the correct answer from the options given below
[a] Both A and R are true and R is the correct explanation of A
[b] Both A and R are true but R is NOT the correct explanation of A
*[c] A is true but R is false
[d] A is false but R is true
Q.58) Arrange the following intermediates in the synthesis of isoprenoids in the right sequence
I. Squalene
II. Farnesyl PP
III. Geranyl PP
IV. Acetyl CoA
V. Mevalonate
Choose the correct answer from the options given below
[a] IV, II, III, I, V
*[b] IV, V, III, II, I
[c] II, III, IV, I, V
[d] V, II, III, I, IV
Q.59) In pharmacokinetic models, the term “Compartment” means
[a] Blood
[b] Individual organ
[c] Extracellular fluid
*[d] Hypothetical pool of tissue
Q.60) A tablet excipient, whose function is to ensure that tablet formulation and ejection can occur with low friction between the solid and the die wall, is called
[a] Glidant
*[b] Lubricant
[c] Anti-adhesive
[d] Binder
