GPAT Exam Paper 2023 with Answer Key

Q.21) Which of the following has been found to act as a male contraceptive without affecting libido and potency

[a] Cyproterone

*[b] Gossypol

[c] Centchroman

[d] Goserelin

Q.22) Match the following concept in List I with parameters in List II

Choose the correct answer from the options given below

[a] 1-[P], 2-[Q], 3-[R], 4-[S]

[b] 1-[T], 2-[S], 3-[R], 4-[Q]

*[c] 1-[S], 2-[P], 3-[R], 4-[T]

[d] 1-[R], 2-[Q], 3-[R], 4-[T]

Q.23) In absence of instruction by the prescriber, unless otherwise directed, the dose given for the mixture preparation should be stated on the label as

[a] One five ml spoonful to be taken three times a day in water

*[b] Two five ml spoonful to be taken three times a day in water

[c] Two five ml spoonful to be taken two times a day in water

[d] One five ml spoonful to be taken two times a day in water

Q.24) The most efficient heat exchange between the particles and flowing air occurs in the

[a] Tray dryer

[b] Vacuum Dryer

*[c] Fluidized bed dryer

[d] Rotary dryer

Q.25) Which of the following emulsifiers has the highest HLB value

[a] Span 80

[b] Acacia

[c] Tween 80

*[d] Sodium lauryl sulfate

Q.26) Predict the wavelength of absorption band in the UV spectrum of the above shown structure

[a] 252 nm

[b] 248 nm

[c] 244 nm

*[d] 240 nm

Q.27) The required amount of adjusting substance required to make a hypotonic solution, isotonic is given by the (Where, W = Adjusting substance, a Freezing point depression of unadjusted solution and b = Freezing point depression of water)

[a] W = (a – 0.52)/b

*[b] W = (0.52 – a)/b

[c] W = (0.52 – b)/a

[d] W = (b – 0.52)/a

Q.28) The following are the processes occurring during flame atomization in atomic absorption spectrometry

P- Volatilization

Q- Ionization

R- Nebulization

S- Desolvation

[T] Dissociation

Arrange the processes in sequential order and choose the correct answer from below

[a] R, Q, P, S, T

[b] R, S, T, Q, P

[c] P, R, S, Q, T

*[d] R, S, P, T,Q

Q.29) Which of the following drug used in the chemotherapy of some types of leukemia, satisfies the statements

Statement I: It is effective orally

Statement II: It has near 100% oral bioavailability

In light of the above statements, choose the correct answer from the options given

below

[a] Asparaginase

[b] Doxorubicin

[c] Mitomycin

*[d] Hydroxyurea

Q.30) Trastuzumab is a/an

*[a] EGFR/HER₂ inhibitor

[b] Angiogenesis inhibitor

[c] EGF receptor (HER) inhibitor

[d] BCR-ABL tyrosine kinase inhibitor

Q.31) Ethyl-2 (p-chlorophenoxy)-2-methyl propionate is IUPAC name of

[a] Fenofibrate

[b] Colestipol

*[c] Clofibrate

[d] Colesevelam

Q.32) A hypertensive patient receiving a drug ‘Y’ for managing BP was prescribed a tricyclic antidepressant. As a result, there was an abolition of the antihypertensive action of ‘Y’.Which of the following drug could be ‘Y’

[a] Atenolol

[b] Captopril

*[c] Clonidine

[d] Diltiazem

Q.33) In the Langmuir Isotherm, following statements are true EXCEPT one

[a] The layer of the gas adsorbed on the solid adsorbent is one molecule thick

[b] Adsorbed layer is uniform all over adsorbent

*[c] No desorption takes place when gas strikes solid surface

[d] No interaction between the adjacent adsorbed molecules takes place

Q.34)

Select the correct product A of the above-given reaction from the four choices given below

[a]

[b]

[c]

*[d]

Q.35) Match the process of reproduction and genetic exchange under column I with the explanation under column II Match List I with List II

Choose the correct answer from the options given below

[a] 1-[P], 2-[R], 3-[S], 4-[Q]

[b] 1-[R], 2-[P], 3-[S], 4-[Q]

[c] 1-[Q], 2-[S], 3-[P], 4-[R]

*[d] 1-[Q], 2-[S], 3-[R], 4-[P]

Q.36) Put the events of acute inflammation in proper sequence

*[a] Accumulation of fluid and plasma at the affected site → intravascular activation of platelets → polymorphonuclear neutrophils → followed by healing

[b] Polymorphonuclear neutrophils → accumulation of fluid and plasma at the affected site → intravascular activation of platelets → followed by healing

[c] Accumulation of fluid and plasma at the affected site → polymorphonuclear neutrophils → intravascular activation of platelets → followed by healing

[d] Intravascular activation of platelets → polymorphonuclear neutrophils → accumulation of fluid and plasma at the affected site → followed by healing

Q.37) Which of the following represents a complete list of products that are offered by a company for Sale

[a] Product Variety

*[b] Product Mix

[c] Product Item

[d] Product Line

Q.38) Shift from ‘Try my product’ to ‘Prefer my brand’ marketing strategy is done at what stage of product life cycle

[a] Introduction

*[b] Growth

[c] Maturity

[d] Decline

Q.39) Which of the following formulations are “Pharmaceutically equivalent”

Match List I with List II

Choose the correct answer from the options given below

[a] P and Q

[b] Q and R

*[c] P and R

[d] Q and S

Q.40) Select the correct set of anticancer drugs that belong to “Pyrimidine and related compounds”

*[a] 5-Fluorouracil, Tegafur, Decitabine, 5-Azacytidine

[b] 5-Fluorouracil, Tegafur, Decitabine, Clofarabine

[c] Tegafur, Decitabine, 5-Azacytidine, Clofarabine

[d] Tegafur, Decitabine, 5-Azacytidine, Pentostatin

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