Pharmaceutical Pastes are semisolid dosage forms that contain one or more drug substances intended for topical/external application to the skin. They are generally very thick & stiff. They differ from ointments in their consistency, as they contain larger amounts of finely dispersed solids (20% to 50%) and so they are thicker and stiffer.
Ointments are semisolid preparations intended for external application to the skin or mucous membranes for protection (calamine, ZnO, TiO2, Silicones) or emollient effect.
|Contains a large amount of finely powdered solids such as zinc oxide, calcium carbonate, starch etc||contains medicaments which are dissolved/suspended/emulsified in the base|
|very thick and stiff so they do not spread easily, result into localizing drug delivery||soft semisolid|
|less greasy||more greasy|
|applied with a spatula or spread on lint||applied on the skin|
|form a protective coating to area where it s applied||used as a protective or emollient for the skin|
|Paste contains a large amount of finely powder which is porous in nature, hence perspiration can escape||used for protection of lesions|
|they are less macerating than ointments||they are more macerating in action|
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