Please find below the question paper of Pharmacist (AMC- Ahmedabad municipal corporation) 2022. Exam contains total 100 MCQ (75 MCQ Pharmacy Section & 25 MCQ General Aptitude).
AMC Pharmacist Question Paper 2022 with Answer Key pdf: Download
Pharmacist Paper 2022 Ahmedabad
Q.1) Relative sweetness of sucrose, to saccharin is
[a] 1:100
[b] 1:300
[c] 1:400
[d] 1:500
Q.2) Following statement is more accurate with respect to limitation of Arrhenius relationship for stability prediction
[a] Order of degradation will alter at higher temperature
[b] Equal moisture concentrations will be mentioned at different temperatures
[c] Less relative humidity & oxygen solubility at higher temperature
[d] Same degradation mechanism may predominate at different temperature
Q.3) Lakes of Dyes available commercially contain maximum upto …..pure dye
[a] 15 %
[b] 10 %
[c] 25 %
[d] 50 %
Q.4) Type 2nd glass container
[a] Suitable for alkaline solution
[b] Most inert classes and show high hydrolytic resistance
[c] Suitable for most acidic and neutral aqueous preparation
[d] Suitable for non-aqueous preparation
Q.5) Dimethyl sulfoxide act as penetration enhancer for topical formulation by
[a] Increasing solubility
[b] Denaturing protein
[c] Increasing trans-epidermal loss
[d] Altering solvent nature of membrane
Q.6) SHICK Test is a sterile filtrate from a culture of
[a] Rechettsia prowazeki
[b] Mycobacterium Diphtheriae
[c] Coryne bacterium Diphtheriae
[d] Actinobacillus mallei
Q.7) Violin gut is obtained from intestine of
[a] Horse
[b] Cat
[c] Sheep
[d] Camel
Q.8) An Excipient Ludipress used for liquid dosage form is a coprocessed excipient of
[a] PticInsi Dextrose monohydrate + Kollidon 30
[b] Lactose monohydrate + Kollidon 30
[c] Lactose monohydrate + Kollidon 30 + Kollidon CL
[d] Dextrose monohydrate + Kollidon 30 + Kollidon CL
Q.9) Pyrogen present in container can be destroyed by heating the containers at
[a] 121 ºC or 15 mins
[b] 121 ºC for 30 mins
[c] 210 ºC for 4 hrs
[d] 210 ºC for 1 hrs
Q.10) Capsule making the Bloom Strength of gelatin is proportional to molecular weight of the gelatin and is a measure of the
[a] Cohensive strength of the solvent molecules
[b] Cohensive strength of the crosslinking that occurs between gelatin molecules
[c] Adhensive strength of gelatin with dipping pins
[d] Adhensive strength of gelatin with other molecules
Q.11) Choose the wrong statement from the following with regard to Amorphous solids
[a] Usually they are anisotropic
[b] They tend to flow when subjected to sufficient pressure
[c] Considered as super cooled fluids
[d] They do not have definite melting point
Q.12) The Crenulation effect on the cell wall is caused by………. Solutions and this effect is………..
[a] Hypertonic, reversible
[b] Hypotonic, reversible
[c] Hypertonic, Irreversible
[d] hypertonic Irreversible
Q.13) The drug concentration between minimum effective concentration (MEC) and maximum safe concentration (MSC) is called
[a] Toxic range
[b] Therapeutic index
[c] Therapeutic range
[d] Therapeutic ratio
Q.14) A metabolite of spironolactone is
[a] Aldosterone
[b] Canrenone
[c] Corticosteroids
[d] Pregnilonone
Q.15) For thermophilic microorganisms, the minimum growth temperature required is
[a] 20 ºC
[b] 37 ºC
[c] 45 ºC
[d] 65 ºC
Q.16) The temperature dependence and theory of viscosity is expressed by the following
[a] Stern-Volmer equation
[b] Arrhenius equation of chemical Kinetic
[c] Higuchi equation
[d] Gibb's equation
Q.17) Which of the following is not a fundamental (primary) factor considered for selection of a location for the construction of Pharmaceutical for chemical plant
[a] Soil
[b] Market for products
[c] Labour supply
[d] Raw materials
Q.18) The following Gram Positive Bacteria species is positive for coagulase test (test for the ability of bacteria to cause blood plasma to clot)
[a] S. epidermidis
[b] S. aureus
[c] S. Saprophyticus
[d] S. lactis
Q.19) The version of GMP in India that describe requirement of factory premises for manufacture of Cosmetic
[a] Schedule M
[b] Schedule M III
[c] Schedule M II
[d] Schedule M I
Q.20) The fungus is also known as opportunity pathogen, often isolated from warm blooded animals
[a] Aspergillusniger
[b] Penicillinum notatum
[c] Penicillinium chrysogenum
[d] Candida albicans
Q.21) Which of the following will result is very closest value to the glomerular filtration rate
[a] Insulin clearance
[b] Albumin clearance
[c] Measure of blood urea nitrogen
[d] Creatinine clearance
Q.22) A widely accepted detector electrode for pH measurement
[a] Platinum wire
[b] Glass electrode
[c] Silver silver chloride electrode
[d] Lanthanum fluoride
Q.23) Staphylococcus aureus is used for the IP assay of
[a] Bleomycin
[b] Doxycycline
[c] Carbenicillin
[d] Kanamycin
Q.24) Increasing the proportion of the dispersed phase of an emulsion by more than 60% may lead to
[a] Cracking
[b] Frothing
[c] Phase inversion
[d] Creaming
Q.25) The rate of drug bioavailability is most rapid when the drug is formulated as a
[a] Solution
[b] Suspension
[c] Gelatin capsule
[d] Tablet
Q.26) State Pharmacy Council should have……… Number of elected members
[a] 5
[b] 6
[c] 7
[d] None
Q.27) The Polymorphs exhibit the following different properties except….
[a] X-ray crystal and diffraction pattern
[b] Melting points
[c] Solubility
[d] Chemical structure
Q.28) Method of study truck distribution pattern is
[a] Mass spectrophotometry
[b] Nuclear Magnetic resonance
[c] Fluorometry
[d] UV visible spectrophotometry
Q.29) Which of the following powder shows the greatest degree of the dustibility
[a] Talcum powder
[b] Lycopodium powder
[c] Fine charcoal
[d] Potato starch
Q.30) The Dispersion of course material by shearing in a narrow gap between static cone and rapidly rotating cone is caused by
[a] Colloidal mill
[b] Electrical dispersion
[c] Peptization
[d] Ultrasonic Irradiation
Q.31) When the concentration of an aqueous sodium solution has the same colligative properties as the solution in question the value so obtained is known as
[a] Normality
[b] Isotonicity value
[c] Molarity
[d] Molality
Q.32) Plasmid is a
[a] Macromolecules involved in the protein synthesis
[b] Circular piece of duplex DNA
[c] A hybrid DNA that is formed by joining piece of DNA
[d] Endogenous substance secreted by one type of cell
Q.33) Centistoke stock is the CGS unit of for the following property
[a] Surface tension
[b] Coefficient of viscosity
[c] Fluidity
[d] Kinematics viscosity
Q.34) A term which describe a cofactor that is finally bound to enzyme
[a] Holoenzyme
[b] Prosthetic
[c] Coenzyme
[d] Transferase
Q.35) When a solid forms a gel more rapidly when gently shaken or otherwise sheared than when allotted to form a gel while the material is kept at rest, the phenomena is known as
[a] Thixotrophy
[b] Rheopexy
[c] Negative rheopexy
[d] Anti-thixotropy
Q.36) In the process of extraction, ethanol is used as a solvent for
[a] Sucrose
[b] Wax
[c] Alkaloids
[d] Gums
Q.37) Human Serum albumin has a molecular weight of
[a] 34000
[b] 65000
[c] 44000
[d] 59000
Q.38) The metabolic function of riboflavin involves the following
[a] FMN & FAD
[b] NADP & NADPH
[c] AMP & ATP
[d] Rectin & Retinine
Q.39) One of the ex officio member of the the pharmacy counselling of India is
[a] Director general of Health Services
[b] Government analyst
[c] Registrar of the state Pharmacy Council
[d] Director general of veterinary Research Institute
Q.40) The schedule in drug and cosmetic act that deals with the requirement and guideline for clinical trial, import and manufacture of new drug is
[a] Schedule O
[b] Schedule M
[c] Schedule F
[d] Schedule Y
Q.41) A retardant material that form a hydrophilic matrix in the formulation of matrix tablet is
[a] HPMC
[b] CAP
[c] Polyethylene
[d] CarNUABA WAX
Q.42) Fraction of administered dose(which may be in form of Astro of salt) of active drug is termed as
[a] Activity factor
[b] Formulation factor
[c] Intrinsic factor
[d] Salt factor
Q.43) An organism which has been implicated as a positive cause of chronic gastritis and peptic ulcer is
[a] Campylobacter Jejuni
[b] E. coli
[c] Helicobacter pylori
[d] Giardia lambia
Q.44) Which of the following is example of invert sugar
[a] Sucralose
[b] Lactulose
[c] Lactose
[d] Sucrose
Q.45) New drug delivery system which is composed of phospholipids that spontaneously form a multilamellar, concentric bilayer vesicles with layers of aqueous media separating the liquid layers
[a] Products
[b] Liposomes
[c] Cosmetic pumps
[d] Nanoparticles
Q.46) Isoniazid is a primary antitubercular agent that
[a] Requires pyridoxine supplementation
[b] Causes of ocular complication that are reversible if the drive is discontinued
[c] Is auto toxic and nephrotoxic
[d] Should never be used due to its hepatotoxicity
Q.47) Decreased risk of atherosclerosis is associated with increase in….
[a] Very low density lipoproteins
[b] Low density lipoprotein
[c] Cholesterol
[d] High density lipoprotein
Q.48) Co-trimoxazole is combination of trimethoprim with sulfamethoxazole. Which of the following statement is correct about cotrimoxazole?
[a] Cotrimoxazole is contraindicated during pregnancy
[b] E most effective ratio of trimethoprim: Cotrimoxazole in plasma 20:1
[c] Trimethoprim: Sulfamethoxazole are administered in a dose ratio of 5:1 to achieve optimal synergistic effect
[d] Cotrimoxazole is ineffective in treating respiratory tract infection
Q.49) Identify the diuretic which cause hyperuricemia, 10 to raise serum calcium and also cause magnesium depletion
[a] Acetazolamide
[b] Furosemide
[c] Mannitol
[d] Chlorothiazide
Q.50) Mitomycin C is an antibiotic isolated from…
[a] Streptomyces peucetius
[b] Streptomyces verticillus
[c] Streptomyces antibiotics
[d] Streptomyces caespitosus
Q.51) Unless otherwise stated in the individual monograph of the Pharmacopoeia, in the disintegration test for enteric coated tablet, first The dissolution is carried out in
[a] 0.1 M HCl
[b] Phosphate buffer
[c] Water
[d] 0.1 M H2SO4
Q.52) One of the following statement with respect to carbachol is not correct identify
[a] It can be administered orally
[b] It possesses both muscarinic and nicotinic action
[c] It is more susceptible to hydrolysis as compared to acetylcholine
[d] The amino group decreases electrophilicity of the carbonyl group
Q.53) The mechanism by which fluoride inhibits dental caries is
[a] By increasing susceptibility to a sit
[b] By increasing the sensitivity of tooth enamel
[c] Decreasing acid solubility of enamel
[d] Increased acid solubility of enamel
Q.54) Lycopodium spore Method can be used to find out percentage purity of crude drug which contain
[a] Multi layered tissue or cell
[b] Well-defined particle which can be counted
[c] oil globules
[d] Characteristic particles of irregular thickness the length of which can be measured
Q.55) Which of the following drugs possess antiplatelet effect
[a] Erythropoietin
[b] Urokinase
[c] Desmopressin
[d] Clopidogrel
Q.56) Choose the correct excipient for enhancing solubility in tablet manufacturer
[a] PEG
[b] Microcrystalline cellulose
[c] Talc
[d] Lactose
Q.57) Plasmodium resistance of chloroquine is due to
[a] Induction of inactivating enzyme
[b] Change in receptor structure
[c] Increase in the activity of DNA repair mechanism
[d] Decreased carrier mediated drug transport
Q.58) Meloxicam belongs to which class of NSAIDs of
[a] preferential Cox 2 inhibitor
[b] Selective Cox 1 inhibitor
[c] Preferential Cox 1 inhibitor
[d] Selective Cox 2 inhibitor
Q.59) Which one of the following is not the property of osmotic diuretic
[a] Undergo limited reabsorption by the renal tubules
[b] Are relatively inert pharmacologically
[c] The inhibit carbonic anhydrase
[d] Freely filtrate at the glomerulus
Q.60) Which one of the following statement is true for cancer cells
[a] Oncoprotein produced by cancer cell act a neighbouring cells
[b] Cancer cells require stimulation by growth factor ([c]
[c] Cancer cells are highly sensitive to growth inhibitory signals
[d] Cancer cells produce oncoproteins in the absence of growth factors for external stimuli
Q.61) Which of the following neurotransmitter is formed in demand and act immediately
[a] Acetylcholine
[b] histamine
[c] Nitric oxide
[d] Adrenaline
Q.62) In one of the following situations metabolic acidosis does not occur
[a] Uncontrolled Diabetes mellitus
[b] Therapeutic administration of acetazolamide
[c] Chronic renal failure
[d] Production of less amount of lactic acid
Q.63) Which one of the following is an organ specific (localize[d] autoimmune disease
[a] Grave disease
[b] Scleroderma
[c] Polyarteritisnodosa
[d] Rheumatoid arthritis
Q.64) Following pairs represent antibiotic and its. Identify Correct pair
[a] Griseofulvin: Bacteria
[b] Polyenes: Fungi
[c] Colistin: Fungi
[d] Macrolides: Actinomycetes
Q.65) As per the drug and cosmetic act 1940, if a drug is not labelled in prescribed manner it is a
[a] Spurious drug
[b] Substandard drug
[c] Adulterated drug
[d] Misbranded drug
Q.66) The measured property of Ayurvedic herb "rasa" indicates
[a] Taste
[b] Post digestive effect
[c] Potency
[d] Physico-chemical properties
Q.67) The general purpose soda line glass is not suitable material for fabricating the container for
[a] Parenteral
[b] Oral solutions
[c] Liquid for external use
[d] Dry powder
Q.68) In colour test for alkaloid colchicine with mineral acid gives……. Colour
[a] Blue
[b] Red
[c] Yellow
[d] Violet
Q.69) Nicotine from tobacco is an alkaloid which is
[a] Oxygen free liquid
[b] Semi solid
[c] Crystalline
[d] Oxygen free solid
Q.70) In solid-solid mixing,_____ is the large scale continuous type mixer
[a] Sigma blender
[b] Ribbon blender
[c] Zigzag blender
[d] Twin shell blender
Q.71) Gold beater skin test is used to detect the presence of____ of class of compounds?
[a] Tannis
[b] Steroids
[c] Glycerides
[d] Resins
Q.72) International organisation for standardization (ISO) standard pertaining to quality system model for Quality Assurance in production, installation and servicing is given under
[a] ISO 9000
[b] ISO 9001
[c] ISO 9002
[d] ISO 9004
Q.73) Blood level monitoring of HbA1c is important in which of the given disease States?
[a] Hypercholesterolemia
[b] Diabetes mellitus
[c] Myocardial interaction
[d] Congestive heart failure
Q.74) Who is the current President of Pharmacy counselling of India?
[a] Dr Montu M.Patel
[b] Dr. B. Suresh
[c] Dr. Pramod Yeole
[d] Dr. Shailendra Saraf
Q.75) With reference to recent development regarding ' recombinant vector vaccine, consider the following statement?
1. Genetic engineering is applied in the development of the vaccine;
2. Bacteria and virus are used as vector ; Which of the statement given above is/are correct
[a] 1
[b] 2
[c] 1&2
[d] Neither 1 or 2
AMC Pharmacist Question Paper 2022 with Answer Key pdf: Download
Pharmacist Paper 2022 Ahmedabad
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